云南大学化学科学与工程学院
专业：无机化学
研究团队：智能分子合成及功能化团队
主讲课程：《无机及分析化学》《AI辅助分子设计与合成》
电子信箱：yule@ynu.edu.cn
受教育经历及工作经历：
2024 -至今，讲师 云南大学 化学科学与工程学院
2019 - 2024，博士 高丽大学（韩国） 有机化学系
2016 - 2019，硕士 云南大学 化学科学与工程学院 分析化学专业
2012 - 2016，学士 云南大学 化学科学与工程学院 应用化学专业
研究领域和兴趣：
(1) 用于疾病诊断的小分子荧光/光声探针的设计与开发；
(2) 用于肿瘤治疗的小分子光敏剂/光催化剂的设计与开发。
学术论文：
(1) Le Yu, Ying Zhou*, Nature: Zinc-mediated regulation of nitrogen fixation through transcription factor filamentation in legumes. Adv. Agrochem. 2024, 3, 263-264 (Latest IF = 11.7)
(2) Le Yu, Syed Ali Abbas Abedi, Jeongjin Lee, Yunjie Xu, Subin Son, Weijie Chi, Mingle Li,* Xiaogang Liu,* Jae Hyung Park,* Jong Seung Kim*, Blending Low-Frequency Vibrations and Push–Pull Effects Affords Superior Photoacoustic Imaging Agents. Angew. Chem. Int. Ed. 2023, 62, e202307797 (IF2025 = 16.9, TOP)
(3) Le Yu, Yunjie Xu, Jong Seung Kim*, Photo-Activated Ferroptosisfor Cancer Therapy: Advances, Challenges, and Prospects. CCS Chem. 2023, 5, 1718-1736 (IF2025 = 9.2, TOP)
(4) Le Yu, Kyung-Woo Lee, Yu-Qiang Zhao, Yunjie Xu, Ying Zhou,* Mingle Li,* and Jong Seung Kim*, Metal Modulation: An Effortless Tactic for Refining Photoredox Catalysis in Living Cells. Inorg. Chem. 2023, 62, 18767-18778 (IF = 4.7, Nature Index)
(5) Le Yu, Yunjie Xu, Jungryun Kim, Jieun Lee, Jong Seung Kim*, A Rational Design of AIE-Active Fluorophore for the Fingerprint. Bull. Korean Chem. Soc. 2023, 44, 516-522 (IF2025 = 2.5)
(6) Le Yu, Yunjie Xu, Zhongji Pu, Heemin Kang, Mingle Li,* Jonathan L. Sessler,* Jong Seung Kim*, Photocatalytic Superoxide Radical Generator that Induces Pyroptosis in Cancer Cells. J. Am. Chem. Soc., 2022, 144, 11326-11337 (IF2025 = 15.6, TOP)
(7) Le Yu, Peter Verwilst, Inseob Shim, Yu-Qiang Zhao, Ying Zhou,* Jong Seung Kim*, Fluorescent Visualization of Nucleolar G-Quadruplex RNA and Dynamics of Cytoplasm and Intranuclear Viscosity. CCS Chem. 2020, 2, 2725-2739 (IF2025 = 9.2, TOP)
(8) Le Yu, Jun Feng Zhang, Mingle Li, Dewei Jiang, Ying Zhou,* Peter Verwilst,* Jong Seung Kim*, Combining viscosity-restricted Intramolecular Motion and Mitochondrial Targeting Leads to Selective Tumor Visualization. Chem. Commun. 2020, 56, 6684-6687 (IF = 4.2, Nature Index)
(9) Le Yu, Yimu Qiao, Lanxi Miao, Yanqi He, Ying Zhou*, Recent Progress in Fluorescent and Colorimetric Sensors for the Detection of Ions and Biomolecules. Chin. Chem. Lett. 2018, 29, 1545-1559 (IF2025 = 8.9)
(10) Pengzhan Wang1, Le Yu1, Jiankang Gong, Jianhua Xiong, Soyu Zi, Hua Xie, Fan Zhang, Zhiqiang Mao,* Zhihong Liu,* Jong Seung Kim*, An Activity-Based Fluorescent Probe for Imaging Fluctuations of Peroxynitrite (ONOO-) in the Alzheimer’s Disease Brain. Angew. Chem. Int. Ed. 2022, 61, e202206894 (IF2025 = 16.9, TOP)
(11) Yu-Qiang Zhao1, Le Yu1, Liping Zhu, Jinsong Liang, Ying Zhou,* Jong Seung Kim*, A Plasma Membrane Polarity Sensor Harnessing Conjoined TICT Modulation and Charge Number Control Strategy. CCS Chem. 2024, 6, 733-748 (IF2025 = 9.2, TOP)
(12) Yu-Qiang Zhao1, Le Yu1, Lanyun Zhang, Huan Liu, Ying Zhou,* Jong Seung Kim*, Activated aggregation-induced emission therapeutics agents for triggering regulated cell death. Aggregate 2024, 5, e503 (IF2025 = 13.7, TOP)
(13) Hao Chu1, Li Yang1, Le Yu1, Jungryun Kim, Jin Zhou,* Mingle Li,* Jong Seung Kim*, Fluorescent Probes in Public Health and Public Safety. Coord. Chem. Rev. 2021, 449, 214208 (IF2025 = 23.5, TOP)
(14) Jun Li1, Yi Zhang1, Pengzhan Wang1, Le Yu1, Jusung An, Ganzhen Deng,* Yao Sun,* Jong Seung Kim*,Reactive Oxygen Species, Thiols and Enzymes Activable AIEgens from Single Fluorescence Imaging to Multifunctional Theranostics. Coord. Chem. Rev. 2021, 427, 213559 (IF2025 = 23.5, TOP)
(15) Yu-Qiang Zhao1, Jiahong Duan1, Le Yu1, Ilwha Kim, Yumin Wang, Yi-Cheng Ma, Cheng-Gang Zou, Ying Zhou,* Jun Feng Zhang,* Jong Seung Kim*, Metabolic Iron Detection Through Divalent Metal Transporter 1 and Ferroportin Mediated Cocktail Fluorogenic Probes. Chem. Commun. 2021, 57, 7902-7905 (IF = 4.2, Nature Index)
科研项目、成果和专利：
无
奖励、荣誉和学术兼职：
(1) 高丽大学（韩国）优秀博士毕业论文（2024）
(2) 三次获得高丽大学（韩国）留学生奖学金（C类）（2020-2022）
(3) 入选留学基金委（CSC）国家建设高水平大学公派研究生项目（2019）
(4) 云南省政府硕士研究生奖学金（2018）
