云南大学化学科学与工程学院
专业：有机化学
主讲课程：制药工艺学，制药分离工程，基础有机化学实验等。
团队：化工实验教学中心、教学团队
电子信箱： liujin@ynu.edu.cn
受教育经历及工作经历： 2006年获云南大学理学硕士学；
2014-2018年，获云南大学理学博士；
2006至今，云南大学化工学院工作。
教学： 先后承担过制药工艺学，制药分离工程，基础有机化学实验，化学元素与生命健康，药物化学实验、应用化学实验、药物制剂与制药工艺学实验、制药工程综合设计实验等教学工作
研究领域和兴趣： 有机合成、药物化学。
主要兴趣为：基于稠杂环化合物的合成方法学研究及生物活性研究。
论文、专著：
近期学术论文：
1) Ting-Ting Guo, Qing-Sheng Zhao, Shu Yang, Tian-Tian Chen, Jin Liu * and Sheng-Jiao Yan.* Rh(III)-catalyzed cyclization of 5-amino-pyrazoleswith maleimides to pyrazoloquinazolines. Chem. Commun., 2025,61, 16846-16849.
2) Jia-Ming Yang, Bi-Na Shao, Xing-Mei Hu, Jian-Bo Ma, Jin Liu* and Sheng-Jiao Yan.* Multicomponent synthesis of functionalized pyrrolo[3,4-e]isoindole-1,3,6,8-tetraones via [2 + 2 + 2] cycloaddition of maleimides with nitroenamines. Org. Chem. Front. 2024, 11, 6144−6149.
3) Shu Yang, Ting-Ting Guo, Jian-Bo Ma, Hui-Ting Jia, Jin Liu,*and Sheng-Jiao Yan* Radical Cascade Reaction of Heterocyclic Ketene Aminals with Thiocyanates Promoted by Visible Light: Synthesis of Functionalized Fused 2-Iminothiazolines. J. Org. Chem. 2024, 89, 13678−13690.
4) Liu Yuan, Jin Liu,* Kun Huang, Siyu Wang, Yi Jin, Jun Lin.* Cascade Reaction of Tertiary Enaminones, KSCN, and Anilines: Temperature-Controlled Synthesis of 2‑Aminothiazoles and 2‑Iminothiazoline. J. Org. Chem. 2022, 87, 9171−9183.
5) Qiang Xiao,‡ Jin Liu,‡ Jia-Hui Nie, Ling-Bin Kong, Jun Lin * and Sheng-Jiao Yan *.Silver-catalyzed cascade reactions of 3-cyanochromone with 1,1-enediamines: synthesis of highly functionalized 2-(pyridin-3-yl)-chromeno[2,3-d]pyrimidines. Org. Chem. Front. 2020, 7, 2035–2039.
6) Jin Liu, Qi Li, Zheng-Mao Cao, Yi Jin, Jun Lin,* and Sheng-Jiao Yan.* Cascade Reaction of Morita−Baylis−Hillman Acetates with 1,1-Enediamines or Heterocyclic Ketene Aminals: Synthesis of Highly Functionalized 2-Aminopyrroles. J. Org. Chem. 2019, 84, 1797−1807. (Supplementary Journal Cover)
7) Jin Liu, Yu-Ling Wang, Ji-Hong Zhang,* Jian-Shan Yang, Han-Chuan Mou, Jun Lin* and Sheng-Jiao Yan* Phosphatase CDC25B inhibitors produced by basic alumina-supported one-pot gram-scale synthesis of fluorinated 2-alkylthio-4- aminoquinazolines using microwave irradiation. ACS Omega 2018, 3, 4534–4544.
8) Jin Liu, Sheng-Jiao Yan* Zheng-Mao Cao, Shi-Sheng Cui and Jun Lin, Synthesis of bicyclic 2-pyridones by regioselective annulations of heterocyclic ketene aminals with anhydride. RSC Adv., 2016, 6, 103057-103064.
9) Jin Liu, Hai-Rui Zhang, Xin-Rong Lin, Sheng-Jiao Yan* and Jun Lin, Catalyst-free cascade reaction of heterocyclic ketene aminals with N-substituted maleimide to synthesise bicyclic pyrrolidinone derivatives, RSC Adv., 2014, 4, 27582-27590.
参编教材：
制药工程专业实验[M]，韦琨，刘金，余正南，李菲，曹秋娥，北京:高等教育出版社，2021年
成果和专利：
1. 严胜骄，刘金，林军，张继红，杨建山，多卤代2-烷硫基-4-氨基喹唑啉类化合物及其制备方法和抗肿瘤应用。授权日期：2020年5月26日，中国，专利号：ZL 2017 1 0702722.5
