
马志强(博士,教授,博士生导师)
专业:有机化学
主讲课程: 有机化学实验
电子信箱:zqma@ynu.edu.cn
马志强长期致力于大位阻多环活性天然产物的高效合成研究,实现了具有挑战性结构的蕊木属单萜吲哚生物碱、密脉木属生物碱、重排甾体/二萜类等多个家族天然产物的结构多样性合成。
受教育经历及工作经历:
2001年本科毕业于兰州大学。2007年博士毕业于中科院上海有机化学研究所。随后在美国德克萨斯大学西南医学中心从事博士后研究。2016年在华南理工大学开始独立科研工作,随后在云南大学开始科研工作。
研究领域和兴趣:
天然药物合成;目标导向的合成方法学研究;药物化学;
代表性论文、专著:
1. Hui Wang, Zhiqiang Ma*, Divergent Synthesis of Kopsia and Structurally Related Monoterpenoid Indole Alkaloids: A Non-Biomimetic Strategy, Acc. Chem. Res. 2025, 58, 2781.
2. Rui Yang; Lihua Wei; Zhiqiang Ma*, Asymmetric synthesis of 3,3-disubstituted oxindoles: methodologies and applications in natural product synthesis, Nat. Prod. Rep. 2026, 43, 1842.
3. Hailong Xu; Yu Yang; Jinghua Wu; Huanfeng Jiang; Zhiqiang Ma*, Divergent asymmetric synthesis of (–)-ganocins A–C and (+)-cochlearol B via a non-biomimetic strategy, Nat. Commun. 2026, https://doi.org/10.1038/s41467-026-78287-1.
4. Xuezhi Li; Wenjie Fang; Qian Hu; Jinyu Tang; Huanfeng Jiang; Kai Chen*; Zhiqiang Ma*, Divergent Asymmetric Synthesis of Glutinosasins A–E, J. Am. Chem. Soc. 2026, 148, 30456–30465.
5. Hui Wang, Lihua Wei, Jiayu Huang, Linsheng Wang, Haobo Peng, Huanfeng Jiang, Jian Wu, Zhiqiang Ma*, Divergent Asymmetric Synthesis of Bonnadiene and ent-Polytrichastrene B, Angew. Chem. Int. Ed. 2025, 64, e202507961.
6. Nanping Zhang, Cheng Wang, Hailong Xu, Ming Zheng, Huanfeng Jiang, Kai Chen, Zhiqiang Ma*, Asymmetric Total Synthesis of Alstrostine G Utilizing a Catalytic Asymmetric Desymmetrization Strategy, Angew. Chem. Int. Ed. 2024, 63, e202407127.
7. Rui Yang, Zeyu Zhou, Huanfeng Jiang, Toh-Seok Kam, Kai Chen, and Zhiqiang Ma*, Asymmetric Synthesis of Arboduridine, Angew. Chem. Int. Ed. 2024, 63, e202316016.
8. Nanping Zhang, Huanfeng Jiang, Zhiqiang Ma*, Concise Synthesis of (±)-Myrioneurinol Enabled by Sequential [2+2] Cycloaddition/Retro-Mannich Fragmentation/Mannich Reaction, Angew. Chem. Int. Ed. 2022, 61, e202200085.
9. Pengquan Chen, Cheng Wang, Rui Yang, Hongjin Xu, Jinghua Wu, Huanfeng Jiang, Kai Chen, Zhiqiang Ma*, Asymmetric Total Synthesis of Dankasterones A and B and Periconiastone A Through Radical Cyclization, Angew. Chem. Int. Ed. 2021, 60, 5512–5518.
10. Cheng Wang, Yubing Pang, Yuecheng Wu, Nanping Zhang, Rui Yang, Ying Li, Pengquan Chen, Prof. Dr. Huanfeng Jiang, Xue-Tao Xu, Toh-Seok Kam, Ting Fan, Zhiqiang Ma*, Divergent Synthesis of Skeletally Distinct Arboridinine and Arborisidine. Angew. Chem. Int. Ed. 2021, 60, 26978–26985.
11. Xu, H.; Wu, J.; Wang, H.; Wang, L.; Jiang, H.; Zhiqiang Ma*, Asymmetric total synthesis of (–)-14-epi-sinugyrosanolide A. Chin. Chem. Lett. 2026, 37, 112018.
12. Zhiqiang Ma†, Xiaolei Wang†, Xiao Wang, Rodrigo A. Rodriguez, Curtis E. Moore, Shuanhu Gao, Xianghui Tan, Yuyong Ma, Arnold L. Rheingold, Phil S. Baran, Chuo Chen*, Asymmetric Syntheses of Sceptrin and Massadine and Evidence for Biosynthetic Enantiodivergence, Science 2014, 346, 219–224. (†equal contribution)
13. Zhiqiang Ma, Xiao Wang, Yuyong Ma, Chuo Chen*, Asymmetric Synthesis of Axinellamines A and B, Angew. Chem. Int. Ed. 2016, 55, 4763–4766.
科研项目、成果和专利:
国家自然科学基金面上项目,2025.1-2028.12。(主持,在研)
国家自然科学基金面上项目,2023.1-2026.12。(主持,在研)
国家自然科学基金面上项目,2021.1-2024.12。(主持,结题)
国家自然科学基金面上项目,2019.1-2022.12。(主持,结题)
国家自然科学基金面上项目,2017.1-2020.12。(主持,结题)
奖励、荣誉和学术兼职:
教育部“长江学者奖励计划”特聘教授(2025)
国家海外高层次人才计划青年项目(2017)
广东省珠江人才计划青年拔尖人才(2018)
Thieme Chemistry Journal Award(2025)